4D Laboratory X-ray Microscopy for the in-Situ Investigation of Drug Release in a Push-pull Osmotic Pump Tablet

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Formulation and in Vivo Evaluation of Once a Day Push-pull Osmotic Tablet

Once a day push pull osmotic tablets containing pramipexole as an antiparkinson’s agent were developed and evaluated for in vivo efficacy. Push pull osmotic tablets are bilayered tablets consisting of pull layer (drug layer) and push layer (polymer layer) coated with semipermeable cellulose acetate membrane containing water leaching pore forming agents. To determine the in vivo efficacy of form...

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ژورنال

عنوان ژورنال: Microscopy and Microanalysis

سال: 2017

ISSN: 1431-9276,1435-8115

DOI: 10.1017/s1431927617006675